格列吡嗪对糖耐量受损者糖尿病进程的影响

Effect of glipizide on progress of diabetes in IGT sufferers

目的为评价药物干预对糖耐量受损(IGT)者的糖尿病进程的影响作用。方法将80例IGT患者平均分为干预组和对照组,干预组口服格列吡嗪控释片,对照组仅一般IGT知识宣教。两组均进行3年临床观察。结果干预组糖尿病的发病率明显低于对照组(P<0.05)。结论格列吡嗪控释片对IGT患者的糖尿病和心脑血管疾病有预防作用。

Objective To evaluate the preventive function of medical intervention in progress of diabetes in sufferers of impaired glucose tolerance （IGT） and cardiovascular diseases. Methods The clinical observation was carried on in 80 IGT sufferers for a period of 3 years. Results The incidence rates of diabetes and coronary heart disease in persons with glipizide extended release tablet treatment group were much lower than those in persons of control group. Conclusion Glipizide extended release tablets have preventive effect on progress of diabetes in sufferer of IGT and occurrence of cerebral and cardiac diseases.