安中宁神胶囊治疗心肝阴血亏虚证失眠疗效观察

The Therapeutic Effect of Anzhongningshen Capsule for Treatment of Insomnia with Yin Deficiency

目的观察安中宁神胶囊对心肝阴血亏虚证失眠的临床疗效。方法将符合心肝阴血亏虚证失眠诊断的病人64例随机分治疗组和对照组,每组32例,治疗组口服安中宁神胶囊每次5粒,每晚1次;对照组口服安慰剂5粒,每晚1次。进行临床疗效和中医证候疗效评价。结果治疗组临床和中医证候总有效率分别是78.1%、90.6%,对照组为28.1%、37.5%,两组比较差异均有统计学意义(P<0.05),且无明显不良反应。结论安中宁神胶囊是治疗心肝阴血亏虚证失眠病人的一种安全有效的治疗药物。

Objective To study the clinical curative effects of Anzhongningshen capsule for treatment of insomnia with xin gan yin xue kuixu. Methods Sixty four patients with insomnia of xin gan yin xue kui xu type were allocated to two groups randomly： The treatment group （ n = 32） treated by Anzhongningshen capsule and the control group （ n = 32） treated by the placebo. The clinical curative effects and the Chinese medicine zhenghou curative effects were assessed after treatment, Results For the treatment group, the total effective rate and Chinese medicine zhenghou effective rate were 78, 1% and 90,6 %, respectively, and for the control group they were 28.1% and 37.5 %, respectively. The total effective rate were significant difference between the two groups （P （0,05）. Few adverse effects were shown in the treatment. Conclusion Anzhongningshen capsule for treatment of insomnia was safe and effective.