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厄贝沙坦和培哚普利治疗老年高血压86例效果比较 被引量:1

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摘要 目的:观察厄贝沙坦和培哚普利治疗老年原发性高血压的效果。方法:将老年原发性高血压86例,随机分为厄贝沙坦组和培哚普利组,在服药前和服药后4周、12月测血压、服药前和服药后12个月测量左室舒张末内径(LVD)、左室舒张期室间隔厚度(IVST)、左室后壁厚度(LVPWT)、左室射血分数(LVEF)、左室短轴缩短率(FS)、二尖瓣口舒张早、晚期血流峰值速度E/A比值。结果:服药4周后,两组血压均明显下降(P<0.01)。治疗12个月后两组LVEF、FS无改变,LVD、IVST、LVPWT及左室重量指数(LVMI)均明显降低(P<0.01),E/A比值明显升高(P<0.01)。结论:厄贝沙坦、培哚普利不仅能有效降低老年人高血压,而且能明显减轻左心室肥厚,改善左室舒张功能,效果相当。
作者 李常杰
出处 《交通医学》 2008年第1期52-53,共2页 Medical Journal of Communications
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