摘要
伯胺的单烷基化在有机合成过程中是非常重要的一类反应。由于伯胺的化学性质较活泼,对其进行烷基化时很难控制在仲胺阶段而易于生成叔胺,因而其单烷基化一般通过间接的方法得到。本文介绍了伯胺单烷基化方法的最新研究进展。
In organic synthesis, mono - alkylation of amines is an important kind of reaction. A further well known and common difficulty in synthesis is the prevention of over - alkylation during the conversion of primary to secondary amines because of their highly activity. Therefore, indirect ways are usually used in the mono - alkylation of amines. In this paper, the recent progress of mono - alkylation of amines has been reviewed.
出处
《化学研究与应用》
CAS
CSCD
北大核心
2008年第3期223-232,共10页
Chemical Research and Application
基金
国家自然科学基金(20472071
20562014)资助项目
南开大学元素有机化学国家重点实验室开放基金(0405)资助项目