饮用水中卤乙酸致癌性的研究进展

Study Advance on Carcinogenicity of Haloacetic Acids in Drinking Water

目前饮用水中主要氯化消毒副产物卤乙酸由于难挥发和难降解,其危害研究特别是致癌性越来越引起人们的重视,为此笔者对饮用水中卤乙酸(主要包括二氯乙酸、三氯乙酸、二溴乙酸)的暴露水平、代谢、致癌性、致癌机制、流行病学研究等方面的研究工作进行了综述,并指出了今后研究的方向。

Haloacetic acids（HAAs） are the major by-product of water disinfection by chlorination and their health effects for carcinogenic activity have attracted more and more interest of researchers due to their high stability because they are hardly degraded and volatilized. The exposure concentration, metabolizing, carcinogenicity, mechanism of tumorigenesis and epidemiologic study about HAAs （mainly including DCAA, TCAA, DBAA） in recent years are discussed in this paper. Finally the research trend is discussed.