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巨噬细胞作用的新概念:正反两面性 被引量:5

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摘要 巨噬细胞的特性主要是一大(最大的吞噬细胞)、二多(受体多、酶及活性产物多),并有三步激活过程(触发、兴奋、充分激活)。其作用有正反两面性,既能参与免疫防护,又能造成不利影响,分别表现为:1、加工提呈抗原辅佐生成免疫,却因提呈差错引起病害;2、吞噬消毁病原异物,但会误伤正常组织和庇护某些病原体侵害;3、协同抗癌,亦可促瘤生长和转移;4、配合增强细胞及体液免疫,而又会抑制生成免疫力。提示应按具体情况区别看待巨噬细胞作用。
出处 《国外医学(免疫学分册)》 北大核心 1990年第2期60-65,共6页 Foreign Medical Sciences(Section of Immunology Foreign Medical Sciences)
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