摘要
联素是主要由脂肪组织分泌的一种活性蛋白质,已经证实其通过直接作用于内皮细胞而起到抗动脉粥样硬化的作用。实验研究结果表明,脂联素具有抗动脉硬化、抗炎和抗糖尿病等特性。尽管脂联素作为一种重要的治疗手段还需要临床进一步地研究,但它可能成为预防和治疗冠状动脉疾病的重要手段。
Adiponectin, a bioactive protein which is secreted specifically by adipose tissue, has been shown to act as an anti-atherosclerotic pr otein by direct effects on endothelial cells. Accumulating experimental evidence indicates that adiponectin possesses anti-atherogenic, anti-inflammato ry and anti-diabetic properties. Although evaluation of adiponectin as a novel therapy will ultimately require studies, it may represent a novel way for the prevention and treatment of coronary artery disease.
出处
《疾病监测与控制》
2008年第3期183-184,共2页
Journal of Diseases Monitor and Control
关键词
联素
抗动脉硬化
心血管疾病
adiponectin
antiatherosclerotic
cardiovascular disease