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乙型肝炎病毒X基因变异的研究现状 被引量:1

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摘要 原发性肝细胞癌(HCC)是世界范围内肿瘤导致死亡的最主要原因之一.我国HCC发生与慢性乙型肝炎病毒(HBV)感染密切相关,HBV基因编码的HBVX蛋白(HBx)为HBV感染和复制所必需.并广泛涉及宿主细胞的增殖、转化和凋亡等过程。因此在HCC发生、发展中可能具有重要的作用。新近研究结果征实肝癌组织中存在着高频自发的HBx基因突变.
出处 《实用医药杂志》 2008年第3期354-356,共3页 Practical Journal of Medicine & Pharmacy
关键词 HBX 突变 肝细胞癌
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