来曲唑与克罗米芬促排卵临床疗效比较被引量：3

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摘要目的比较来曲唑(Letrozole,LE)与克罗米芬(C lom iphene,CC)促排卵的疗效。方法将非多囊卵巢综合征(polycystic ovarian syndrom e,PCOS)排卵异常患者68例(139周期)随机分成2组,每组分别应用LE(2.5 mg,1次/d,连用5 d)、CC(50 mg,1次/d,连用5 d)促排卵,观察比较两组的卵泡发育、子宫内膜生长、宫颈粘液性状、排卵率、妊娠率等。结果LE组注射人绒毛膜促性腺激素日子宫内膜厚度、宫颈粘液评分及排卵率均高于CC组,平均优势卵泡个数低于CC组,差异有统计学意义(P<0.05);妊娠率高于CC组,黄素化未破裂卵泡综合征(LUFS)发生率低于CC组,但差异无统计学意义(P>0.05);两组均未出现卵巢过度刺激综合征。结论LE有促卵泡生长的作用,成熟卵泡破裂排卵率高,对生殖系统及全身的副反应小。

作者孙玉兰聂树霞刘培淑

机构地区新泰市人民医院齐鲁医院

出处《社区医学杂志》 2008年第5期11-12,共2页 Journal Of Community Medicine

关键词来曲唑克罗米芬促排卵子宫内膜

分类号 R711.6 [医药卫生—妇产科学]

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