口服布洛芬和对乙酰氨基酚对小儿上呼吸道感染伴发热的疗效观察

Observation on the Curative Effect of Brufen and Paracetamol for Children Acute Infective Fever

目的观察布洛芬和对乙酰氨基酚治疗小儿急性感染伴发热的疗效。方法对261例急性感染性发热患儿,体温≥38.5℃者随机分为两组,布洛芬组145例,应用布洛芬治疗,对乙酰氨基酚组116例用对乙酰氨基酚治疗,对两组行退热疗效分析。结果布洛芬组在疗效、最大作用时间及持续时间上,明显优于对乙酰氨基酚组,两组比较有显著性差异,P<0.01。结论口服布洛芬退热效果确切,且明显优于对乙酰氨基酚,具有较强而持久的疗效。在儿科布洛芬作为解热药使用是安全、有效且疗效持久的。

Objective To observe the curative effect of Brufen and Paracetamol for child infective fever. Methods 261 children with acute infective fever, temperature ≥ 38.5 ℃, were randomly divided into 2 groups ： Brufen group （ n = 145 ） and Paracetamot group （ n = 116 ）, the effects in removing fever of the 2 groups were compared. Results The curative effect, the maximum of effect time and effect duration of Brufen group were much superior to those of Paracetamol group, the difference between the 2 groups was of significance （ P 〈 0.01 ）. Conclusion Brufen is of obvious effect in removing fever and the effect is stronger and more persistent than Paracetamol.