1H-MRS在颅脑感染诊断及鉴别诊断中的应用

Application of 1H magnetic resonance spectroscopy in diagnosis and differential diagnosis of cerebral infection

目的通过总结8例颅脑感染与13例胶质瘤的1H-MRS表现,分析1H-MRS在颅脑感染诊断与鉴别诊断中的应用价值。方法8例颅脑感染与13例胶质瘤(1～2级6例,3～4级7例)均进行MRS检查,测定各代谢物的波峰下面积。结果脑脓肿NAA/Cr及Cho/Cr分别为4.114±3.637和3.084±0.933,肿瘤NAA/Cr及Cho/Cr分别为1.064±0.823和5.987±4.380,并且3例脑脓肿出现氨基酸(AA)峰。结论1H-MRS能够为颅脑感染的诊断及与肿瘤的鉴别诊断提供有价值的信息。

Objective To study the application of single voxel proton magnetic resonance spectroscopy in diagnosis and differential diagnosis of cerebral infection according to manifestations of the 8 patients with cerebritis and 13 patients with gliomas. Methods The patients including 8 cerebral abscess and 13 gliomas were examined with MRS. And the quantity of the NAA.Cho.Cr.Lip.Lac.AA were measured and copmared. Results There were differences between cerebral abscess and tumors on MRS. NAA/Cr and Cho/Cr of abscess were 4.114±3.637 and 3.084±0.933. NAA/Cr and Cho/Cr of tumors were 1.064±0.823 and 5.987±4.380. There was amino acids （AA） could be seen in some of cerebral abscess. Conclusion 1H magnetic resonance spectroscopy can supply important information in diagnosis cerebral infection and differentiate information with tumor.