婚检者生殖道支原体感染及药敏分析

Analysis of Mycoplasma Infection and Drug Sensitivity in Premarital Consultation Urogenital Tract

目的:了解本地区婚前检查者生殖道支原体感染及药敏情况。方法:运用药敏试剂盒对本地区152对婚前检查进行生殖道解脲支原体(Uu)和人型支原体(Mh)培养和药敏分析,支原体采用广东珠海丽珠试剂有限公司提供的培养鉴定进行操作。结果:支原体培养阳性86例(28.3%),单一Uu感染68例(79.1%),单一Mh感染例4例(4.6%),Uu和Mh混合感染例14例16.3%)。支原体对药物的敏感性由高到低依次是:克拉霉素93.5%,美满霉素91.4%,强力霉素87.0%,阿齐霉素56.5%,司帕沙星50.4%,交沙霉素39.2%,左氧氟沙星47.9%,氧氟沙星34.8%。最低是罗红霉素15.2%。结论:本地区婚前检查者支原体感染率较高;支原体对克拉霉素最为敏感。

Objective To survey mycoplasma infection in premarital consultation urogenital tract and analyze the drug sensitivity of mycoplasma in Guangzhou. Methods Ureaplasma urealyticum （Uu） and Mycoplasma hominis （Mh） were detected in 152 cases of premarital consultation urogenital tract, infection by means of mycoplasma culture and drug sensitivity reagent kit. Results A total of 86 eases were mycoplasma-positive （positivity rate of 28.3% ）, including 68 Uu-positive cases （79. 1% ）,4 Mh-positive cases （4.6%） and 14 cases positive for both Uu and Mh （16.3%）. The mycoplasma to the medicine sensitivity from high to low in turn is clarithromycin （93.5%）, minocycline （91.4%）, doxycycline （87.0%）, azithrumycin （56.5%）, sparfloxacin （50.4%）, josamycin （39.2%）, levofloxacin （47.9%）, roxithromycinid （ 15.2% ）. Conclusion This area the percentage of mycoplasma infection in premarital consultation was high ; clarithromycin is most sensitive to mycoplasma.