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东菱克栓酶治疗脑梗死并发梗死后出血14例原因分析

Analysis of Factors Related to Hemorrhagic Infarction Treated with Batroxobin(DF-521)
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摘要 收集资料完整的我院2002年1月~2006年3月使用东菱克栓酶(DF—521)治疗急性脑梗死继发梗死后出血(HI)患者共14例,对引起梗死后出血的原因进行分析。分析结果表明,长期高血压、糖尿病控制不良及大面积脑梗死、栓塞是使用DF—521后引起梗死后出血的高危因素,高龄、合并应用抗凝药物及用药距发病时间较长、皮质性脑梗死为引起梗死后出血的危险因素,应严格掌握适应症,选择合适的病例,用药期间严密地监测病人的凝血功能,减少出血的发生。 Objective.. The reasons that caused hemorrhagic infarction were analysed in 14 patients after using DF-521. The high risk "factors were as followers., hypertension, hyperglycemia, embolism and large size of the cerebral infarction. Additionally, old age,delayed therapy time and cerebral infarction were also risk factors. To avoid bleeding after using DF-521, it was absolutely necessarily to control the risks that induce the occurrence of side-effects, and it, s also important to monitor the level of FIB properly.
出处 《中国伤残医学》 2007年第6期23-24,共2页 Chinese Journal of Trauma and Disability Medicine
关键词 东菱克栓酶 脑梗死 梗死后出血 Batroxobin(DF--521) Cerebral infarction Hemorrhagic infarct
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