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肝纤维化基因治疗新策略 被引量:3

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出处 《肝脏》 2007年第6期495-497,共3页 Chinese Hepatology
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  • 1Qing He Nie Yong Qian Cheng Yu Mei Xie Yong Xing Zhou Yi Zhan Cao The Center of Infectious Disease Diagnosis and Treatment of PLA,Tangdu Hospital,Forth Military Medical University,Xi’an 710038,Shaanxi Province,ChinaDr,Qing He Nie graduated from Qinghai Medical College as a doctor in 1983,got master degree at Beijing 302 Army Hospital in 1993,got doctor degree at the Third Military Medical University in 1998,engaged in postdoctoral research at the Fourth Military Medical University from 1998 to 2000,now an associate professor,specialized in clinical and experimental research of infectious diseases,had more than 90 papers published,coauthor of ten books,first author of one book..Inhibiting effect of antisense oligonucleotides phosphorthioate on gene expression of TIMP-1 in rat liver fibrosis[J].World Journal of Gastroenterology,2001,7(3):363-369. 被引量:73
  • 2Wei-DaZheng Li-JuanZhang Mei-NaShi Zhi-XinChen Yun-XinChen Yue-HongHuang Xiao-ZhongWang.Expression of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-1 in hepatic stellate cells during rat hepatic fibrosis and its intervention by IL-10[J].World Journal of Gastroenterology,2005,11(12):1753-1758. 被引量:34
  • 3[1]Hui AY,Friedman SL.Molecular basis of hepatic fibrosis.Expert Rev Mol Med 2003; 2003:1-23
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  • 5[3]Safadi R,Friedman SL.Hepatic fibrosis-role of hepatic stellate cell activation.Med Gen Med 2002; 4:27
  • 6[4]Gressner AM.Cytokines and cellular crosstalk involved in the activation of fat-storing cells.J Hepatol 1995; 22:28-36
  • 7[5]Friedman SL.Molecular mechanisms of hepatic fibrosis and principles of therapy.J Gastroenerol 1997; 32:424-430
  • 8[6]McGuire RF,Bissell DM,Boyles J,Roll FJ.Role of extracellular matrix in regulating fenestrations of sinusoidal endothelial cells isolated from normal rat liver.Hepatology 1992; 15:989-997
  • 9[7]Schuppan D,Ruehl M,Somasundaram R,Hahn EG.Matrix as modulator of stellate cell and hepatic fibrogenesis.Semin Liver Dis 2001; 21:351-372
  • 10[8]Farrar MA,Schreiber RD.The molecular cell biology of interferon-gamma and its receptor.Annu Rev Immunol 1993; 11:571-611

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