老年冠心病合并代谢综合征患者的冠状动脉病变特点

The Features of Coronary Artery Lesion Changes in the Aged Coronary Heart Disease Patients with Metabolic Syndrome

目的探讨老年冠心病合并代谢综合征患者的冠状动脉病变特点。方法检测54例老年冠心病合并代谢综合征患者与108例老年冠心病不合并代谢综合征患者的腰围、空腹血糖、血脂、血压及冠状动脉造影。结果合并代谢综合征组冠状动脉血管多支病变、弥漫性病变及闭塞性病变较不合并代谢综合征组多(P>0.05),且主要累及左主干和左回旋支(P>0.05);合并代谢综合征组左心室功能减退高于不合并代谢综合征组(P>0.05)。结论合并代谢综合征患者在多重心血管危险因素聚集下,冠状动脉呈多支病变且病变严重,积极干预心血管危险因素,对防止冠心病的发生、发展,改善预后有重要的意义。

Aim To study characteristics of coronary artery pathological changes in the aged coronary heart disease（CHD） patients with metabolic syndrome.Methods A total of 162 aged cases with coronary heart disease were divided into two groups according to the status of being combined with metabolic syndrome（MS groups,54 patients） or not（non-MS groups,108 patients）.Coronary arteriongraphy（CAG） scoring and assay of cardiac function,waist circumference,blood pressure,fasting blood glucose（FBG）,triglyceride（TG）,total cholesterol（TC）,high density lipoprotein cholesterol（HDLC）,low density lipoprotein cholesterol（LDLC） were performed in all subjects and the left ventricular rejection fraction（LVEF） was measured with echocardiography.Results The MS patients suffered more from multi-vessel lesions,diffuse lesions and completely obstructive lesions（ P〉 0.05）,LVEF decreased in MS groups.Conclusion The MS patients with multiple cardiovascular-risk factors,often have multi-branch lesion and more severe lesions.To treat cardiovascular risk factors actively is very important to prevent the CHD and improve its prognosis.