子宫全切围术期抗生素应用的研究

Investigation on effect of prophylactic antibiotics during operative period of hysterectomy

目的探讨子宫全切围术期应用抗菌药物预防术后感染的医学及经济学意义。方法采用前瞻性随机应验方法,比较围术期预防性应用抗菌药物组与常规传统用药两组在切口感染、平均住院日、住院费用等方面的差异。结果围术期用药组与常规用药两组相比,前者术后感染率较低,且平均住院日短,住院费用低。结论子宫切除围术期应用抗菌药物是预防术后感染的理想方法。

Objective To investigate the elect of the prophylactic application of antibiotics during the perio- perativetime in the patients for hysterectomy. Methods Retrospective combined prospective study, the data of two groups of patients who received prophylactic application of antibiotics in the periope rative period or received tradition al routine medication in the postoperative time were collected;the infection rate,average hospitalization days, average hospitalization expenses between the groups were compared. Resalts The use of antibiotics in the period perative period group had reduced wound infection rate,got shorter average hospitalization days and lower average hospitalization expenses as compared with the group received prophylactic antibiotics ratively traditional routine medication. Conclusions It is recommended to prevent infection through the prophylactic application of antibiotics during the perioperative period and by taking synthetic measures for the hysterectomic patients.