骨碱性磷酸酶对婴幼儿佝偻病早期诊断的临床研究

Study on early diagnosis of rickets on Infants and young children by determination of the Bone alkaline phosphatase

目的探讨骨碱性磷酸酶(BALP)在婴幼儿佝偻病早期诊断中的临床意义。方法对123例维生素D(VitD)缺乏性佝偻病患儿进行BALP检测并设立正常对照组,对BALP≥250u/L者,结合临床进行血清钙(Ca)、磷(P)、碱性磷酸酶(AKP)和X线比较分析。结果BALP检测具有敏感、特异、简单、快速、经济等优点。结论BALP是目前佝偻病早期诊断有价值实验方法,值得普及和推广。

Objective： To study the clinical idea on early diagnosis of rickets by determination of the Bone alkaline phosphatase On infants and young children. Methods ： The Bone alkaline phosphatase （BALP） of 101 infants of Vitamin D deficiency were detected and building the normal control group , It is analyzed and compared with with clinical character, sercem Ca, P, AKP and X -ray for infants of BALP≥250U/L. Results： It is discovered to be sensitive, spectifical, simple and economical way on BALP determination. Conclusion： It is one of the most valuable way for early diagnosis of rickets and to be worth spreading.