中铁四局计免门诊疫苗免疫后抗体水平监测结果分析

Analysis of Antibody Level after vaccination at A EPI Vaccination Clinic

目的了解在中铁四局计免门诊接受麻疹、乙肝、甲肝、风疹、腮腺炎疫苗接种后抗体水平,评价该计免门诊疫苗接种质量。方法采用酶联免疫吸附试验对接种麻疹疫苗、甲肝疫苗、风疹疫苗和腮腺炎疫苗后的儿童进行IgG抗体检测;采用放免SPRIA监测方法对接种乙肝疫苗后的儿童检测HBS-Ab抗体,把该计免门诊的抗体监测结果与所在地总体资料比较。结果该计免门诊麻疹疫苗(1针)、风疹疫苗和腮腺炎疫苗免后抗体水平高于总体资料检测水平,差异无显著性意义(P>0.05),麻疹疫苗(2针)、乙肝疫苗和甲肝疫苗免后抗体水平与总体资料检测水平差异有显著性意义(P<0.01)。结论该计免门诊疫苗接种质量高,接种工作方法可行。

Objective To understand antibody level of measles, hepatitis B, hepatitis A, rubella, mumps after vaccination so as to evaluate the quality of the EPI clinic. Methods ELISA method was used to detect measles and hepatitis A, rubeLla and mumps IgG antlbody. SPRIA method was used to detect HBS - Ab. A particular out - patient information was compared with the local general information. Results Antibody level of measles vaccine （ a needle ） , mumps and rubeLla vaccine after vaccination was compared with the overall level of antibodies. The difference was not statistically significant （ P 〉 0.05）. There was significant difference between antibody level measles （2 -pin） , hepatitis B and hepatitis A after vaccination at the clinic and the overall level of antibodies （ P 〈 0.01 ）. Conclusion The vaccination is of high quality and the working methods is piacticalele at the clinic.