乙肝六项模式在各个年龄组的分布及结果分析

Investigation of 6 Modes of HBV Distribution Among Sevral Age-Groups

目的探讨乙肝6项模式在各个年龄组的分布比例及同组男女和各组之间含HBsAg阳性模式阳性率差异。方法采用ELISA试剂盒对3731例住院及门诊患者进行乙肝6项检测。结果全阴性与单独第2项阳性模式所占比例,0～7岁组>56岁以上组>26～55岁组>8～25岁组,分别为83.2%、73.8%、62.7%、62.5%;男女含HBsAg阳性模式阳性率比较,0～7岁组没有显著性差异(χ2=0.08,P>0.75)、8～25岁组有显著性差异(χ2=4.39,P<0.05)、26～55岁组有极显著性差异(χ2=10.3,P<0.005)、56岁以上组没有显著性差异(χ2=2.77,P>0.05);各组之间HBsAg阳性模式阳性率有极显著性差异(χ2=36.98,P<0.005)。结论8～25岁组、26～55岁组乙肝患病率较高,应间隔3～5年加强乙肝疫苗的注射、并注意养成良好的卫生习惯、加强体育锻炼。

Objective To study distribution of 6 modes of HBV among several age - groups and difference of positive HBsAg rate between men and women in same group and difference of positive HBsAg rate between several age - groups. Methods 6 modes of HBsAg were detected by ELISA in a series of 3731 patients. ResuIts The rates of all negative and Anti - HBsAg positive were 83.2% , 73.8% ,62.7% and 62.5% ,resectively in 0 -7 years old group,over 56 years group ,26 - 55 years group and 8 - 25 years old group. There was no significant difference of positive HBsAg rate between men and women of 0 - 7 years old group（Х^2 = 0.08,P 〉 0.75 ） and the same result in over 56 years old group（Х^2 = 2.77 ,P 〉 0.05 ）. There was a significant difference of positive HBsAg rate between men and women both in 8 - 25 years old group（Х^2 = 4.39,P 〈 0.05 ） and in 26 - 55 years old group （Х^2 = 10.3, P 〈 0. 005 ）. Again, positive HBsAg rate was significant difference between several age - groups（Х^2 = 36. 98,P 〈 0. 005 ）. ConcIutions Prevalence rate of HBV is higher in 8 - 25 years old group and 26 - 55 years old group ,so vaccine of HBV should be administrated in every 3 -5 years.