复发性卵巢交界性肿瘤保留生育功能手术的临床疗效观察

The results of fertility conservative surgery for recurrent borderline ovarian tumors

目的:了解复发性卵巢交界性肿瘤患者施行保留生育功能手术后的月经、生育功能以及肿瘤复发情况。方法:回顾分析2000至2006年浙江大学附属妇产科医院收治的复发性卵巢交界性肿瘤6例患者施行保留生育功能手术后的月经、生育以及复发情况。结果:(1)6例患者中5例月经正常;(2)3例患者共妊娠4次,其中3次为足月妊娠并分娩活婴,1次流产,自然妊娠率达50%;(3)平均随访时间为32个月(6～72个月),其中1例复发,但未发生与肿瘤相关的死亡。结论:对年轻有强烈生育要求的复发性卵巢交界性肿瘤患者仍可考虑施行保留生育功能手术,术后自然妊娠率高,但需严密随访。

Objective：To evaluate the menstruate, fertility and recurrence results of fertility conservative surgery for women with recurrent borderline ovarian tumors. Methods：Six pa- tients with recurrent borderline ovarian tumors who had conservative surgery from 2000 to 2006 were identified from Women＇s hospital, Zhejiang University. Results： （1） In the six women, five patients had normal menstrual function. （2） Three women had successful pregnancies, with a total of 3 live births and 1 abortion. The spontaneous pregnancy rate was 50%. （3） The mean duration of follow-up was 32 months（ range ,6 -72）. One of the six patients with recurrent borderline ovarian tumors developed recurrence once more. But no disease related deaths occurred. Conclusion： The second conservative surgery for patients with recurrent borderline ovarian tumors should still be considered for women who are young and desire preservation of fertility. The spontaneous pregnancy rate is satisfactory. However, careful follow-up is needed to detect recurrent disease.