单纯钾停跳氧合血持续灌注不降温心脏直视手术(附160例报告)

Potassium-induced Arrest with Continuous Oxygenated Warm Blood Cardioplegia for Myocardial Protection during Normothermic Open Heart Surgery

应用钾停跳、氧合血持续灌注心肌保护、不降温体外循环行心脏直视手术１６０例，手术均顺利，术后无低心排综合征、无严重心律失常发生。全组死亡２例（１．２５％）。部分病例进行了ＬＤＨ１／ＬＤＨ２、ＣＫ－ＭＢ及血清乳酸测定，与低温体外循环组比较无统计学明显差异（Ｐ＞０．０５）。作者认为，此方法临床效果满意，值得进一步研究、推广应用。

Aim:To evaluate the effect of potassium-induced warm blood cardioplegia on myocardial protection during normothermic open heart surgery.Method:160 patients with heart disease underwent open heart surgery using the technique of potassium-induced arrest with warm blood cardioplegia.Results:The hospital mortality was 0.13%.Postoperative complications included respiratory failure and renal failure.No low cardiac output or severe arrhythmia occurred postoperatively.Comparing with cold crystalloid cardioplegia,the level of serum lactate and myocardial specific enzymes(LDH 1/LDH 2,CK MB)didn't show any difference.Conclusion:Potassium-induced arrest with continuous oxygenated warm blood cardioplegia is a feasible,effective and safe technique for myocardial protection during CPB.