BOO1对氯硝柳胺杀螺增效作用的研究

SYNERGISTIC MOLLUSCICIDAL EFFECT OF B001 COMBINED WITH NICLOSAMIDE

本文报道了B001对钉螺的杀灭作用和对氯硝柳胺杀螺的增效作用，结果发现B001有一定杀螺作用，6．25mg／L的杀螺率为100％，其LD50为0．6130mg／L。与氯硝柳胺组成混合液，在0．4mg／L的B001溶液中，氯硝柳胺的LD50由单独浸杀的0．0598mg／L降为0．0238mg／L，杀螺效果提高了2．51倍。B001与氯硝柳胺组成0．5：1、1：1、1．5：1、2：1的复方时，其共毒系数（CTC）分别为119．8、134．8、153．8、127．2。B001对氯硝柳胺杀螺有明显的增效作用。

Molluscicidal effect of compound B001[O,O’-diethyl-O”-(phennitrile oxime) thiophosphate] against Oncomelania hupensis hupensis and the synergistic effect combined with niclosamide are reported. The results showed that the snail mortality of compound B001 reached 100% at the conentration of 6.25 mg/L and with LD50 of 0.6130mg/L. The LD50 of niclosamide combined with 0. 4mg/L compound B001 was 0.0238 mg/L while the LD50 of single niclosamide was 0.0598 mg/L.The cotoxicity coefficients (CTC) wer 119.8, 134.8, 153 .8, 127. 2 respectively when compound B001 combined with niclosamide in 0.5:1, 1:1, 1.5:1, 2:1 Showing compound B001 combined with niclsoamide had significant synergistic molluscicidal effect.