摘要
目的:观察夜交藤对自由活动大鼠睡眠时相的影响。方法:按20g/kg(生药量)的剂量,经灌胃途径给予大鼠,连续给药7天后描记大鼠皮质脑电。结果:夜交藤水煎液能延长自由活动大鼠总的睡眠时间(P<0.01),在睡眠时相上主要表现为延长SW S1和SW S2,对REMS没有明显的影响。结论:夜交藤水煎剂对正常大鼠睡眠周期有一定的影响,具有改善睡眠的作用。
Objective： To invest the effects of Caulis Polygoni Multiflori. decoction on sleeping state of free -moving rats. Methods： After intragastric administration of Caulis Polygoni Muhiflori. decoction （equivalent to 20g/kg crude drug） for 7 days, Polysomnography was used to record the changes of EEG of different sleeping states in rat, Results ： After administration of Caulis Polygoni Muhiflori. decoction, total sleeping time was increased in free- moving rats（ P 〈 0.01 ）, SWS1 and SWS2 was obviously increased on sleeping states but REMS changed insignificantly. Conclusion： The decoction of Caulis Polygoni Multiflori, has influence on sleeping state of normal rats and has improving - sleep effect,
出处
《辽宁中医杂志》
CAS
北大核心
2008年第3期466-467,共2页
Liaoning Journal of Traditional Chinese Medicine
基金
黑龙江省自然科学基金资助项目(D0317)
关键词
脑电图
夜交藤
睡眠时相
中医药疗法
实验研究
polysomnography
caulis polygoni multiflori, decoction
sleeping state
TCM therapentivs
experimental study
