亚急性脊髓联合变性13例临床分析

Clinical Characteristic of 13 Cases with Subacute Combined with Degeneration

目的探讨亚急性脊髓联合变性的临床特征。方法分析了13例SCD的临床表现。结果肢体感觉异常和深感觉障碍是SCD最常见的症状和体征;胃肠疾病可能是SCD一个主要病因;SCD患者不一定都由维生素B12缺乏引起;肌电图检查有助于早期诊断;磁共振成像可以明确脱髓鞘部位且有助于评估预后。结论肌电图和磁共振检查对SCD的诊断和治疗起重要作用。

Objective To study the clinical characteristics of subacute combined with degeneration. Methods The clinical manifestations of 13 cases with subacate combined with degeneration were analysed. Results Parasthesias of the limbs and diminished vibration and position sensations were the most common symptoms and signs; gastric and intestinal disease were a main cause of subacute combined with degeneration; some patients were caused by vitamin B12 deficiency, but not all; the examinations of electromyography （EMG） was available to diagnose early; magnetic resonance imaging showed compatible evidence of demyelination changes in the spinal cords and helped to evaluate prevention. Conclusion The examinations of electromyography and magnetic resonance imaging could play an important role in the diagnosis and treatment of subacute combined with degeneration.