妊娠合并糖尿病患者母婴并发症临床分析

Diagnosis and treatment of maternal and neonatal complications in diabetes complicating pregnancy and gestational diabetes mellilus

目的分析糖尿病合并妊娠患者母婴并发症发生情况及结局。方法收集50例糖尿病合并妊娠患者（A组）及50例妊娠期糖尿病患者（B组）的临床资料，并比较两组妊娠结局。结果A组孕期平均血糖（7．77±2．57）mmol／L、糖化血红蛋白（6．67±1．83）％，均高于B组[（5．73±1．52）mmol／L、（4．89±0．87）％]（P〈0．05）；A组妊娠期高血压综合征、胎膜早破、酮症酸中毒、早产、羊水过多、胎儿宫内窘迫和剖宫产率均明显高于B组（P〈0．05）；A组孕妇胎婴儿巨大儿、新生儿低血糖、胎死宫内、呼吸窘迫综合征（RDS）、畸形的发生率均明显高于B组（P〈0．05）。结论糖尿病合并妊娠对孕妇及胎儿有较大危害，要加强对其孕前、孕期及孕后的管理。

Objective To explore the maternal and neonatal complications of diabetes complicating pregnant, and related diagnosis and teratment. Methods The data of 50 cases of pregnant patients complicated with diabetes （A group） and 50 cases gestational diabetes mellitus（GDM）（B group） were analyzed retrospectively. Maternal and neonatal complications including pregnant-induced hypertension, premature rupture of membrane, DKA, pretermdelivery, polyhydramnios, fetal distress, fetal death, rate of caesarean section, postpartum hemorrhage, fetal macrosomia, neonatal hypoglycemia,RDS, and congenital malformations were compared between the two groups. Results The pregnancy complications exclude postpartum hemorrhage in A group were significant higher than those in B group. The incidences of fetal macrosomia,neonatal hypoglycemia, fetal death were also higher in A group when compared to B group（P 〈 0.05 ）. Conclusion Pregnant women complicated with diabetes have morese svere hazards on mother and neonatal, we should enhance managements to these women in progestation, duration of pregnancy, and postlabour.