慢性前列腺炎合并抑郁及睾酮低下患者的临床观察及处理

Clinical treatment of chronic prostatitis patients with depression and testosterone deficiency

目的探讨慢性前列腺炎(CP)合并抑郁及睾酮低下患者的治疗对策,分析CP患者精神心理状况与睾酮水平的关系。方法采用NIH-CPSI评分表、Zung焦虑量表(SAS)、抑郁量表(SDS)及PADAM评分表对106例CP患者进行慢性前列腺炎症状、精神心理状况和睾酮缺乏症状评估,测定其血清总睾酮和游离睾酮水平,并给予睾酮补充治疗。结果睾酮补充治疗可明显降低CP患者NIH-CPSI、SAS、SDS及PADAM评分分值,患者的自觉症状、性功能状况及与社会的融合性也明显提高。结论CP患者的精神心理状况与睾酮缺乏互为因果,睾酮补充治疗可明显改善患者的自觉症状和精神心理状况。

Objective To evaluate the effect of the clinical treatment of the chronic prostatitis patients with depression and testosterone deficiency, and to investigate the relationship between the psychiatric disorders and testosterone deficiency of these patients. Methods The NIH-CPSI, Self-rating Anxiety Scale（SAS）, Self-rating Depression Scale （SDS） and Partial androgen decline in the aging male Scale （PADAM） were employed to appreciate the status of 106 patients with CP. Testosterone level were determined and testosterone supplement therapy（TST） was undertaken. Results The NIH-CPSI, SAS, SDS and PADAM scores were significantly descended after TST, symptoms of the patients were abated, and erectile function was improved. Conclusion In patients with chronic prostatitis there is a causality between the psychiatric disorders and testosterone deficiency, and the TST is the effective treatment method.