摘要
高脂血症鹌鹑口服文蛤肉水解液20、10g/kg2w后,能明显抑制血清总胆固醇(TC)和甘油三酯(TG)的升高,提高高密度脂蛋白胆固醇(HDL-C)的含量。4w后,能不同程度地降低肝胆固醇(Ch)及TG含量;给药3w后,对正常及高脂血症鹌鹑的全血粘度均有降低作用;并且能抑制家兔体外ADP诱导的血小板聚集。结果显示,文蛤肉水解液具有明显降血脂、降低血液粘度及抑制血小板聚集的作用。
Hydrolysate of Meretrix meretrix soft tissue (HMST ) (20, 10g/kg ,po.for 14d ) could markedly inhibit the increase of serum total cholesterol(TC)and triglyceride(TG),enhance the content of high density lipoprotein cholesterol(HLD-C) ;reduced cholesterol(Ch)of the liver(for 28d)in hyperlipimic quail ;and it could also reduce whole blood viscosity in normal and hyperlipemic quail (for 21d).In addition.it could suppress the platelet aggregation induced by ADP in rabbits in vitro. The results show that HMST obviously decreased blood lipid and whole blood viscosity .inhibited platelet aggregation.
出处
《中国海洋药物》
CAS
CSCD
1997年第2期21-24,共4页
Chinese Journal of Marine Drugs
关键词
文蛤
水解液
药效
高脂血症
Meretrix meretrix
blood lipidsiblood viscosity iplatelet aggregation
