MSCT肺动脉成像高浓度低剂量对比剂应用的可行性研究

Feasibility of multislice CT angiography of pulmonary artery with high concentration and low dose contrast media

目的:探讨多层螺旋CT肺动脉成像中使用高浓度、低剂量对比剂的可行性。方法:40例被检查者分为两组,A组为采用300mgI/ml对比剂,剂量为100ml、生理盐水30ml;B组为采用400mgI/ml对比剂,剂量为60ml、生理盐水30ml。注射流速均为4ml/s,行胸部肺动脉同层动态扫描,计算肺动脉主干峰值时间(time to peak)、强化峰值(peak contrast enhancement)以及强化CT值大于200HU起始时间(Tb200)和持续时间(T200)。结果:肺动脉主干到达峰值的时间,B组明显早于A组、强化峰值,B组明显高于A组,且均有显著性差异;T200及Tb200,两组间也存在显著性差异。结论:在多层螺旋CT肺动脉成像检查中,使用高浓度、低剂量对比剂可以满足临床需要。

Objective：To study the feasibility of multislice CT angiography of pulmonary artery with high concentration and low dose contrast media.Methods：Forty patients with chest dynamic enhanced using multislice CT body-perfusion protocol were divided into 2 groups according to the kind and dosage of contrast media as follows： Group A,300 mgI/ml contrast media 100 ml and saline 30 ml;Group B,400 mgI/ml contrast media 60 ml and saline 30 ml.Injected rate was 4 ml/s.The time-density curve（TDC） of the trunk of pulmonary artery was delineated.The time to peak,peak contrast enhancement,the time of begin to 200 HU（Tb200） and the time of duration on 200HU（T200） were recorded.Results：As for the time to peak and peak contrast enhancement of the trunk of pulmonary artery,group B was earlier and higher than group A.The T200 and Tb200 had significant difference between the two groups.Conclusion：It is feasible to use high concentration and low dose contrast media for multislice CT pulmonary artery angiography.