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新型人类冠状病毒HKU1的研究进展 被引量：3

Progress on the Study of New Types of Human Coronavirus HKU1
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摘要 在高发病率和高致死率的严重急性呼吸综合征(SARS)的启发下,许多学者开始致力于冠状病毒的研究。2004年以及2005年初就发现了两种新的主要与呼吸道疾病相关的人类冠状病毒,其中HCoV-HKU1(Human coronavirus HKU1)由中国香港学者2005年发现,其感染多发生在有基础疾病的患者,目前该病毒的检测基础方法主要是逆转录-聚合酶链反应,其在全球的分布和流行情况还不太明确。现就人类冠状病毒的发现历史,HCoV-HKU1毒粒的形态结构及其基因组结构特征、遗传变异等方面做一综述。 Illuminated by the high morbidity and mortality of severe acute respiratory syndrome（SARS）,lots of scholars began to dedicate themselves to the study of coronavirus.During 2004 and the beginning of 2005,they had discovered two new types of human coronavirus mainly accociated with respiratory tract diseases.HCoV-HKU1 was firstly described by Hong Kong University in 2005,and was the latest human coronavirus discovered.HCoV-HKU1 cases present among patients with major underlying diseases.At present,RT-PCR is the basic detection method for HCoV-HKU1.The global distribution and epidemiology of HCoV-HKU1 were still not very clear.In this article,we summarized the history of human coronavirus,and the information of human coronavirus HKU1 such as the virion morphous,the genome organization,the variability and so on.
作者 吴小青(综述) 伍严安(审校)
机构地区 福建医科大学省立临床学院
出处 《医学综述》 2008年第6期861-863,共3页 Medical Recapitulate
基金 福建省自然科学基金项目(F0310042)
关键词 冠状病毒 HCoV-HKU1 呼吸道疾病 Coronavirus HCoV-HKU1 Respiratory tract disease
分类号 R373.1 [医药卫生—病原生物学]
  • 相关文献

参考文献21

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二级参考文献10

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共引文献18

同被引文献18

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引证文献3

二级引证文献6

医学综述
2008年 第6期

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