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热休克蛋白与冠状动脉粥样硬化斑块稳定性的研究

Research Progress of Heat Shock Protein and Coronary Atherosclerotic Plaque's Stability
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摘要 热休克蛋白(HSP)又称应激蛋白,是一组具有重要生理功能,进化上高度保守的蛋白质分子家族。冠状动脉粥样硬化是急性冠脉综合征的主要病理基础。文章综述HSP与动脉粥样硬化不稳定斑块间的联系,借以认识HSP在不稳定斑块发生、发展过程中的作用,从新的角度预测急性心血管事件的发生。 A heat shock protein（HSP）,also known as stress proteins,is a group of important physiological functions and evolutionarily highly conserved protein molecule family.Coronary artery atherosclerosis is the main pathological basis of acute coronary syndrome.This article summarizes the relationship between HSP and atherosclerotic unstable plaque to recognize HSP＇s role in the development of unstable plaque and to predict the occurrence of acute cardiovascular events in a new sight.
作者 黄恩泽 陈新山
机构地区 华中科技大学同济医学院法医学系
出处 《医学综述》 2008年第6期877-879,共3页 Medical Recapitulate
关键词 热休克蛋白 冠状动脉综合征 动脉粥样硬化 不稳定斑块 Heat shock protein Coronary artery syndrome Atherosclerosis Unstable plaque
分类号 R322.1 [医药卫生—人体解剖和组织胚胎学] R541.1 [医药卫生—心血管疾病]
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医学综述
2008年 第6期

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