摘要
研究了苦参总碱的体内抗肿瘤作用。通过苦参总碱对荷S180肉瘤和H22肝癌小鼠的瘤重和生存时间影响的研究,观察了苦参总碱的小鼠体内抗肿瘤作用。结果表明:苦参总碱剂量中生药含量在8g/kg以上能抑制荷S180和H22小鼠瘤体的生长,其抑制率可达30%,从而延长荷瘤小鼠的生存时间,表明苦参总碱具有明显的抗肿瘤作用。
Antitumor effects of Alkaloids from Sophora flavescens on weight and survival time of S180 and H22 -bearing mice in vitro were studied. The results showed that alkaloids from Sophora flavescens could inhibit the growth of cancer cells of S180-bearing mice and prolong the survival time of H22 -bearing mice.
出处
《现代食品科技》
EI
CAS
2008年第3期220-222,共3页
Modern Food Science and Technology
关键词
苦参总碱
抗肿瘤作用
荷瘤小鼠
alkaloids of Sophora flavescens
antitumor effect
tumor-bearing mice