芍桐三花散敷脐治疗类风湿性关节炎200例临床研究

Shaotong Sanhua San Applied on Umbilicus for Clinical Treatment of 200 Cases of Rheumatic Arthritis

目的:探讨自拟的芍桐三花散敷脐治疗类风湿性关节炎的临床疗效及其安全性。方法:将300例RA患者随机分为两组,治疗组200例给予芍桐三花散敷脐治疗,对照组100例口服MTX、萘普生胶囊。结果:治疗组200例、对照组100(97*)例控显率分别为55.00%(110例)、25.77%(25例),有效率分别为30.0%(60例)、39.18%(38例),两组比较,差异显著(P<0.01);两组肿胀、压痛、握力、晨僵、关节整体功能积分治疗前后相比较,分别为P<0.01、P<0.05,治疗组明显优于对照组。结论:自拟的芍桐三花散敷脐治疗RA有较好的临床疗效,奏效快,安全尚无毒副作用。

Objective：to investigate effectiveness and safety of self-formulated umbilicus applied Shaotong Sanhua San for treatment of rheumatic arthritis （RA）. Methods：300 RA patients were randomly divided to treated group （200 cases） applied with the powder, and control group （100 cases） orally given MTX and Naproxen. Results：the treated group showed an excellent rate of 55.00% （110 cases） and an effective rate 30.0% （60 cases） in comparison with the control group＇ s excellent rate of 25.77% （25 cases） and effective rate of 39.18% （38 cases）. The difference was significant （P 〈0.01 ）. Both groups, in such indices as swelling, tenderness, grip strength, morning stiffness, general marks for joint function improved significantly after treatment. In the meantime the treated group re- markably excelled the control group. Conclusion：the self-formulated umbilicus applied Shaotong Sanhua San is immediately effective and adverse function free for treating RA.