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冠状动脉微循环的功能评价 被引量：10

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摘要 冠状动脉（冠脉）微循环是指心脏微动脉和小静脉之间的血液循环，是心肌细胞与血液进行物质交换的重要场所。冠脉微循环的功能状态可以直接影响心脏功能和代谢，它对于心血管疾病的发生、发展、疗效及预后等具有重要影响，而心血管疾病本身也是造成或加重微循环结构和功能的障碍的因素。同时，随着对冠心病患者冠脉再通术后“无复流”现象认识的加深；
作者 陈章炜 钱菊英
机构地区 复旦大学附属中山医院心内科上海市心血管病研究所
出处 《中华心血管病杂志》 CAS CSCD 北大核心 2008年第3期276-279,共4页 Chinese Journal of Cardiology
基金 国家自然科学基金资助项目（30671998） 上海曙光追踪计划资助项目（06GG03）
关键词 冠状动脉微循环 冠脉微循环功能 “无复流”现象 微血管性心绞痛 心血管疾病 心脏X综合征 心肌血流灌注 血液循环
分类号 R686 [医药卫生—骨科学]
  • 相关文献

参考文献29

  • 1Sambuceti G, L'Abbate A, Marzilli M. Why should we study the coronary microcirculation? Am J Physiol Heart Circ Physio1,2000, 279 : H2581-H2584.
  • 2Yokoyama I, Ohtake T, Momomura S, et al. Reduced coronary flow reserve in hypercholesterolemic patients without overt coronary stenosis. Circulation, 1996,94:3232-3238.
  • 3魏盟,马士新,王齐冰,樊冰,严卫,潘翠珍.冠状动脉微血管病患者的三支冠状动脉血流储备的差异[J].临床心血管病杂志,2003,19(6):352-353. 被引量：6
  • 4Murata E, Hozumi T, Matsumura Y, et al. Coronary flow velocity reserve measurement in three major coronary arteries using transthoracic Doppler echocardiography. Echocardiography, 2006, 23:279-286.
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  • 6Takeuchi M, Lodato JA, Furlong KT, et al. Feasibility of measuring coronary flow velocity and reserve in the left anterior descending coronary artery by transthoracic Doppler echocardiography in relatively obese American population. Echocardiography,2005,22:225-232.
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二级参考文献35

  • 1Yokoyama I, Ohtake T, Momomura S, et al. Reduced coronary flow reserve in hypercholesterolemic patients without overt coronary stenosis. Circulation, 1996, 94:3232--3238.
  • 2Kyriakidis M K, Dernellis J M, Androulakis A E, et al. Changes in phasic coronary blood flow velocity profile and relative coronary flow reserve in patients with hypertrophic obstructive cardiomyopathy. Circulation,1997, 96:834--841.
  • 3Antony I, Nitenberg A. Coronary flow reserve is similarly reduced in hypertensive patients without any other coronary risk factors and in normotensive smokers and hypercholesterolemic patients with angiographically normal coronary arteries. Am J Hypertens, 1997, 10:181--188.
  • 4White C W, Kern M J. Clinical applications of Doppler coronary flow reserve measurement. Am J Cardiol,1993, 71: 10D--16D.
  • 5Suzuki H, Takeyama Y, Koba S, et al. Small vessel pathology and coronary hemodynamics in patients with microvascular angina. Int J Cardiol, 1994, 43:139--150.
  • 6Garot P, Teiger E, Dupouy P, et al. Coronary microcirculation and cardiovascular pathology. Drugs, 1999,58:23--31.
  • 7Gavin J B, Maxwell L, Edgar S G. Microvascular involvement in cardiac pathology. J Mol Cell Cardiol,1998, 30: 2531--2540.
  • 8Ofili E O, Labovitz A J, Kern M J. Coronary flow velocity dynamics in normal and diseased arteries. Am J Cardiol, 1993, 71: 3D-9D.
  • 9魏盟 邵志丽 等.冠状动脉造影正常者测定冠状动脉血流储备的意义[J].中华内科杂志,2000,39:189-189.
  • 10Thielmann M, Dorge H, Martin C, et al. Myocardial dysfunction with coronary microembolization: signal transduction through a sequence of nitric oxide, tumor necrosis factor-alpha, and sphingosine. Cite Res, 2002, 90: 807-813.

共引文献35

同被引文献95

引证文献10

二级引证文献42

中华心血管病杂志
2008年 第3期

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