低强度半导体激光照射对小鼠腹腔巨噬细胞功能的影响

Effects of Low-energy Semiconductor Laser Irradiation on Peritoneal Macrophages in Mice

目的:观察低强度650nm半导体激光对小鼠腹腔巨噬细胞吞噬功能的影响。方法:用不同功率和照射时间的650nm半导体激光辐照小鼠腹腔巨噬细胞,采用中性红吞噬实验测定巨噬细胞的吞噬能力。结果:在适当的激光功率和照射时间下巨噬细胞的吞噬能力有显著性增强。结论:低强度650nm半导体激光照射对小鼠腹腔巨噬细胞有激活作用,可增强其免疫活性。

Objective： To investigate the effect of low-energy 650nm semiconductor laser irradiation on peritoneal macrophages in mice. Methods： Peritoneal macrophages in mice was irradiated with the semiconductor laser using various output power and time. The phagocytosis ability of peritoneal macrophages to the dye neutral red was measured. Results ： Semiconductor laser in certain dosage could significantly augment the peritoneal macrophage phagocytosis ability. Conclusion： The present study suggested that low-energy 650nm semiconductor laser could be capable of enhancing immune function of peritoneal macrophages of mice.