原发性乳腺恶性淋巴瘤28例临床分析

Clinical analysis of 28 cases of primary breast malignant lymphoma

为了分析原发性乳腺恶性淋巴瘤(PBL)的临床病理特点、诊断、治疗方法及预后,回顾性分析28例PBL的病理分型、临床特点、诊断和治疗方法。28例均为女性,非霍奇金淋巴瘤27例,其中B细胞来源占89.5%,T细胞来源占10.5%,中位年龄44岁,5年生存率为22.5%。初步研究结果提示,PBL的预后与分期和治疗方式有关,手术+放化疗的综合治疗模式较好,局部切除应作为手术治疗的首选。

In order to analyze the clinical pathological characteristics, diagnosis,treatment and prognosis factors in primary breast lymphoma（PBL）, the clinical data of 28 cases PBI. were analyzed retrospectively. All patients were female with average age of 44 years. Twenty-seven cases were non Hodgkin lymphoma with B-cell lineage （89.5%） and T-cell lineage （10.50%）. The overall 5-year survival rate was 22.5 %. In conclusions, the prognosis of PBL might be related with the stage and treatment modality. Operation combined with chemoradiotherapy might be the best treatment method. Local excision should be the first choice in surgery.