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衰老对大鼠脑区氨基酸水平的影响 被引量:5

The Effects of Aging on Amino Acid Level in Different Region of Rat Brain
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摘要 本文测定了正常青龄组(3月龄)和老龄组(20月龄)大鼠不同脑区(皮层、小脑海马、纹状体和下丘脑)谷氨酸、天门冬氨酸、甘氨酸、r-氨基丁酸和牛磺酸的含量。结果表明:在衰老过程中大鼠某些脑区谷氨酸、天门冬氨酸、甘氨酸和牛磺酸水平显著降低;而纹状体γ-氨基丁酸含量则显著升高。 Content of glutamic acid(Glu), aspartic acid(Asp), glycine (Gly),GABA and taurine (Tau) were measured in five brain regions(cortex, cerebellum, hippocampus, striatum, hypothalamus) of young and old Wistar rat hespectively. Glu, Asp, Gly and Tau level was found to be significantly lower in some brain regions of aged rat, whereas GABA content significantly higher in striatum of aged rat.
出处 《氨基酸和生物资源》 CAS 1997年第3期32-34,共3页 Amino Acids & Biotic Resources
关键词 衰老 脑区 氨基酸 神经递质 动物实验 Aging Rat regions Amino acid
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