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复合药物局部注射治疗瘢痕疙瘩临床观察 被引量:4

Clinical study on keliod treatment with intralesional injection of 5-fluorouracil and corticosteroid
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摘要 目的:观察得宝松联合5-氟尿嘧啶局部注射治疗增生性瘢痕和瘢痕疙瘩的疗效。方法:对37例增生性瘢痕和瘢痕疙瘩患者采用得宝松和5-氟尿嘧啶皮损内注射。结果:37例患者,临床治愈15例,显效21例,无效1例,总有效率为97.3%。结论:得宝松联合5-氟尿嘧啶治疗增生性瘢痕和瘢痕疙瘩疗效显著。 Objective To explore the effect of intalesional injection of fluorouracil and corticosteroid. Methods Thirty-seven patients were treated with intralesional injection of 5-UF and corticosteroid. Results fifteen pationts of thirty-seven keloids achieved complete remission,twenty-one patients mostly remission,one patient no remission.The efficasy of inhibiting keliod was 97.3. Conclusion In hibition of keliod angiogenesis with intralesional injection of 5-FU with corticosteroid injection can achieve satisfactory result.
出处 《中国美容医学》 CAS 2008年第3期420-421,共2页 Chinese Journal of Aesthetic Medicine
关键词 瘢痕疙瘩 得宝松 5-氟尿嘧啶 Keloid 5-fluorouracil Corticosteroid
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参考文献5

  • 1Mustoe TA, Cooler RD, Cold MH, et al. International clinical recommendations on scar management[J].Plast Reconstr Surg, 2002,110:560-571.
  • 2Apikian M,Googman O.Intralesional 5-fluorouralntralesiocil in the treatment oF keloid scars [J]. Australas J Dermatol,2004,45(2):140-143.
  • 3武晓莉,刘伟,曹谊林.低浓度5-氟尿嘧啶抑制血管增生在瘢痕疙瘩综合治疗中的作用初探[J].中华整形外科杂志,2006,22(1):44-46. 被引量:44
  • 4Manuskiatti W,Fitzpatrick RE.Treatment response of keloidal and hypertrophic sternotomy scars: comparison among intralesional corticosteroid, 5-fluorouracil. and 585-nm flashlamp-pumped pulsed-dye laser treatments[J]. Arch Dermatol.2002,138 (9): 1149-1155.
  • 5Gupta S,Kalra,Arndt KA,et al. Efficacy and safey of intralesional 5-fluorouracil in the treatment of keloids[J].Dermatology,2002,204:130-132.

二级参考文献6

  • 1Urioste SS,Arndt KA,Dover JS.Keloids and hypertrophic scars:review and treatment strategies.Semin Cutan Med Surg,1999,18:159-171.
  • 2Berman B,Bieley HC.Keloids.J Am Acad Dermatol,1995,33:117-123.
  • 3Alster TS,Handrick C.Laser treatnent of hypertrophic scars,keloids,and striae.Semin Cutan Med Surg,2000,19:287-292.
  • 4Fitzpatrick RE.Treatment of inflamed hypertrophic scars using intralesional 5-FU.Dermatol Surg,1999,25:224-232.
  • 5Mustoe TA,Cooter RD,Gold MH,et al.International clinical recommendations on scar management.Plast Reconstr Surg,2002,110:560-571.
  • 6Gupta S,Kalra A.Efficacy and safety of intralesional 5-fluorouracil in the treatment of keloids.Dermatology,2002,204:130-132.

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