运动对糖尿病视网膜病变患者生化指标的影响

Effect of Exercise on the Biochemical Indices of Patients with Diabetic Retinopathy

目的研究运动对糖尿病患者视网膜病变的改善作用。方法对50例糖尿病视网膜病变患者给予正规运动、药物加饮食干预,分别在入组时、入组后3个月、6个月和1年时检测生化指标的变化,评价视网膜病变的改善情况。结果运动治疗3个月后糖尿病视网膜病变患者FFA、FBG、PBG、TG和HbA1c开始下降,和入组时比较有统计学意义(P<0.01)。运动治疗3个月后,糖尿病视网膜病变患者HDL显著增高,和入组时比较有统计学意义(P<0.01)。结论正规运动、药物和饮食治疗可以明显改善糖尿病患者视网膜病变。

Objective To study the effect of exercise in improving the pathological changes of diabetic retinopathy. Methods Fifty patients with diabetic retinopathy were enrolled in this study. The patients were urged to engage in regular exercises in addition to medication and dietary interventions. At the start of this study and 3, 6, and 12 months during the study, the patients were examined for changes of the biochemical index,and the pathological changes of the diabetic reti-nopathy were examined. Results The free fatty acids （FFA）, fasting blood glucose （FBG）, postprandial blood glucose （PBG）, triglycerides （TG） and glycosylated hemoglobin Alc （HbAlc） decreased significantly in these patients after 3 months of exercises in comparison with the baseline levels（ P 〈0.05）. Significantly increased high-density lipoprotein （HDL） level was noted in the patients after exercises for 3 months as compared with the baseline level（ P 〈0.05）. Conclusion Regular exercises, medication and dietary interventions may significantly improve the pathological changes of the retina in diabetic patients.