高压氧联合激素治疗急性一氧化碳中毒后迟发性脑病的临床研究

Clinical study of combining hyperbaric oxygen with hormone in the treatment of DEACMP

目的:探讨急性一氧化碳中毒后迟发性脑病(DEACMP)的治疗方法。方法:将72例DEACMP患者随机分为观察组36例和对照组36例。对照组施以烟酸、脑活素及内科对症处理等常规治疗。观察组在此基础上,采取高压氧联合激素治疗。结果:观察组和对照组有效率分别为94.44%、75.00%。观察组疗效明显高于对照组(2χ=5.74,P<0.01)。结论:高压氧联合激素等治疗DEACMP疗效较好,是临床较理想的治疗方法。

Objective：To explore the treatment method of delayed encephalopathy after acute carbon monoxide poisoning （DEACMP）. Methods：72 patients with delayed encephalopathy after acute carbon monoxide poisoning were randomly divided into control group（n=36） treated according to routine principle （including nicotinic acid ,cerebrolysin etc.）and research group（n=36） treated with hyperbaric oxygen combined with hormone. Results：the total effective rate was 94.44% in research group, the total effective rate was 75.00% in control group, the total effective rate was higher in research group than that in control group （P〈0.01）. Conclusion：Combining hyperbaric oxygen with hormone was more effective in the treatment of delayed encephalopathy after acute carbon monoxide poisoning. It was an ideal treatment.