原发性十二指肠肿瘤16例诊断与治疗

Diagnosis and treatment of primary duodenal neoplasms neoplasms:A report of 16 cases

目的：提高原发性十二指肠肿瘤的诊断及治疗水平。方法：总结1999-2006年经病理证实16例原发性十二指肠肿瘤,分析其病理特征与临床表现、诊断及治疗的关系。结果：行胰十二指肠切除术8例,1例术后7个月死亡;1例术后2个月痊愈,出院后失去随访;生存3年者4例,5年者2例。肠段切除（球部、水平部肿瘤）2例,1例存活3年,1例存活2年后失访。姑息性手术者6例于术后3-11个月死亡;2例仅行探查活检,均于术后6个月内死亡。结论：早期诊断的关键是提高对本病的认识,对可疑患者,应作相应特殊检查,确诊后及时手术,方可提高疗效。

Objective：To improve the diagnosis and treatment of primary duodenal neoplasms. Methods：The records of 16 patients with primary neoplasms of the duodenum were confirmed by pathology during 1999 - 2006. The relationship between pathologic characteristics and clinical symptoms, diagnosis and therapy were reviewed. Results： Eight cases underwent pancreatodenectomy ：4 cases survived 3 years,2 cases survived 5 years;2 cases underwent segmental duodenectomy, 1 survived 3 years and 1 survived 2 years; 6 cases underwent palliative surgery; died 3 - 11 months after operation. Two cases who recieved biopsy died in six months after operation. Conclusions：The understanding of duodenal neoplasms is the key factor for early diagnosis. The appropriate exaninations are necessary for suspected patients. Once the diagnosis is confirmed,the result of surgical treatment is improved.