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PGC-1α和能量代谢的关系 被引量：5

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作者 胡小磊 石建华 项平
机构地区 蚌埠医学院第一附属医院内分泌科
出处 《蚌埠医学院学报》 CAS 2008年第2期248-251,共4页 Journal of Bengbu Medical College
基金 国家自然科学基金资助项目(30440026)
关键词 糖尿病 2型 过氧化物酶体增殖物激活受体γ辅激活因子1α 肥胖 能量代谢 综述
分类号 R587.1 [医药卫生—内分泌]
  • 相关文献

参考文献29

  • 1Puigserver P,Wu Z, Park CW, et al. A cold-inducible coactivator of nuclear receptors linked to adaptive thennogenesis [ J]. Cell, 1998,92 (6) :829 - 839.
  • 2Lin J, Puigserver P, Donovan J, et al. Peroxisome prolifemtoractivated receptor gamma coactivator 1 beta ( PGC-lbeta), a novel PGC-1-related transcription coactivator associated with host cell factor[J]. J Biol Chem,2002,277(3) :1 645 - 1 648.
  • 3Andersson U, Scarpulla RC. PGC-1 -related coactivator, a novel, serum-inducible coactivator of nuclear respiratory factor 1- dependent transcription in mammalian ceils [ J]. Mol Cell Biol, 2001,21 ( 11 ) .3 738 - 3 749.
  • 4Boss O, Bachman E, Vidal-Puig A, et al. Role of the beta ( 3 )- adrenergic receptor and/or a putative beta(4 )-adrenergic receptor on the expression of uncoupling proteins and peroxisome proliferator-activated receptor-gamma coactivator-1 [ J ]. Biochem Biophys Res Commun, 1999,261 ( 3 ) :870 - 876.
  • 5Gomez-Ambrosi J,Fruhbeck G, Marunez JA. Rapid in vivo PGC-1 mRNA upregulation in brown adipose tissue of Wistar rats by a beta(3 )-adrenergic agonist and lack of effect of leptin [J]. Mol Cell Endocrinol ,2001,17 6 (1-2 ) :85 -90.
  • 6Daitoku H, Yamagata K, Matsuzaki H, et al. Regulation of PGC-1 promoter activity by protein kinase B and the forkhead transcription factor FKHR [J]. Diabetes, 2003,52 ( 3 ) :642 - 649.
  • 7Chan LL,Chen Q,Go AG,et al. Reduced adiposity in bitter melon (Momordica charantia)-fed rats is associated with increased lipid oxidative enzyme activities and uncoupling protein expression[ J]. J Nutr,2005,135(11) :2 517 -2 523.
  • 8Terada S, Kawanaka K, Goto M, et al. Effects of high-intensity intermittent swimming on PGC-lalpha protein expression in rat skeletal muscle [ J ], Acta Physiol Scand,2005,184 ( 1 ) :59 - 65.
  • 9Pilegaard P, Saltin B, Neufer PD. Exercise induces transient transcriptional activation of the PGC-lalpha gene in human skeletal muscle [ J ]. J Physiol,2003,546 ( 3 ) : 851 - 858.
  • 10McGee SL,Hargreaves M. Exercise and myocyte enhancer factor 2 regulation in human skeletal muscle[ J]. Diabetes,2004,53 ( 3 ) : 1 208-1 214.

二级参考文献5

  • 1Puigserver P,Wu Z,Park CW,et al.A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis.Cell,1998,82:829-839.
  • 2Andersen G,Urhammer SA,et al.Mutation analysis of peroxisome proliferator-activated receptor-γ coactivator-1(PGC-1) and relationships of identifyied acid polymorphisms to Type Ⅱ diabetes mellitus.Diabetologia,2001,44:2220-2226.
  • 3Lacquemant C,Chikri M,Boutin P,et al.No association between the G482S polymorphism of the proliferator-activated receptor-γ coactivator-1 (PGC-1) gene and Type Ⅱ diabetes in French Caucasias.Diabetologia,2002,45:602-603.
  • 4Hara K,Tobe K,Okada T,et al.A genetic variation in the PGC-1 gene could confer insulin resistance and susceptibility to Type Ⅱ diabetes.Diabetologia,2002,45:740-743.
  • 5苏林,杨克恭,陈松森.一种新的辅激活因子——PGC-1[J].生命的化学,2003,23(2):92-94. 被引量：4

共引文献2

同被引文献69

引证文献5

二级引证文献22

蚌埠医学院学报
2008年 第2期

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