增强FLAIR T2WI诊断脑膜转移瘤的价值

Value of Contrast Enhanced FLAIR T_2WI in the Diagnosis of Meningeal Metastasis

目的:探讨脑膜转移瘤的MRI表现及增强后FLAIR序列T2WI的诊断价值。方法:回顾性分析20例脑膜转移瘤患者的病例资料,其中硬脑膜转移瘤5例,软脑膜转移瘤15例。所有病例行常规MRI平扫及SE T1WI和FLAIR序列T2WI增强扫描并进行对比分析。结果:MRI平扫检出6例,病灶边界均显示不清;MRI增强扫描检出所有病例,SE-T1WI上病变主要表现为脑膜的线状和/或结节状强化,FLAIR T2WI对软脑膜转移瘤病灶范围的显示更清楚,可鉴别强化的血管与病变。结论:MRI增强扫描是诊断脑膜转移瘤的重要检查方法,增强后FLAIR序列T2WI与SE T1WI同时使用,可提高对软脑膜转移瘤的检出率及诊断准确性。

Objective： To evaluate the value of conventional MRI and post-contrast FLAIR T2WI images in the diagnosis of meningeal metastasis. Methods：20 cases with meningeal metastasis （including 5 cases with dural metastasis and 15 cases with leptomeningeal metastasis） were enrolled in this study. Pre-contrast and post-contrast （SE T1 WI, FLAIR T2 WI） MRI in all patients were acquired and analyzed retrospectively. Results： Metastatic lesions were found in 6 cases on pre-contrast MR images,with ill-defined margin. On post-contrast SE T1 WI, the meningeal lesions were demonstrated as linear or nodular enhancement. The leptomeningeal metastatic lesions showed more clearly on the post-contrast FLAIR T2WI images which was also helpful in the differentiation of leptomeningeal metastases from normally enhanced blood vessels. Conclusion：Enhanced MRI plays an important role in the diagnosis of meningeal metastasis,the detection rate and diagnosis accuracy of leptomeningeal metastasis could be improved by using SE T1 WI combined with FLAIR T2 WI sequences after con- trast enhancement.