Treacher Collins综合征眼部畸形的综合整复

Synthetic plastic treatment of ocular malformations in the patients with Treacher Collins syndrome.

目的 探讨以眶颧再造和上睑带蒂皮瓣转位的方法治疗Treacher Collins综合征的眼部畸形。方法 从2001～2006年，采用下睑缘切口或冠状切口进路，应用Medpor人工骨材料进行眶颧再造和上睑带蒂皮瓣转位治疗Treacher Collins综合征眼部畸形4例。结果 4例整复再造术均获成功，所有病例对术后的外形改善满意，眶颧部分得到修复，随访3个月至5年，未发现感染或人工材料局部外露等并发症。结论 眶颧再造和上睑带蒂皮瓣转位修复术是治疗Treacher Collins综合征眼部畸形的重要部分，Medpor是目前最理想的人工骨材料，它具有良好的组织相容性，易塑形、无排异不吸收、不复发等优点，可以避免采用自体骨供区的损伤等潜在的并发症。

Objective To discuss a synthetic plastic method to correct orbitozygomatic and ocular malformations in the patients with Trcacher Collins syndrome. Methods From 2001 to 2006, 4 cases of Treacher Collins syndrome were treated with orbitozygomatic reconstruction and musculocutaneous flap transposition from the upper eyelid. In operations, the lateral orbital rim and the mala were exposed by the bicoronal incision or the subciliary incision. The zygomatic bone and lateral wall of the orbit were reconstructed and augmented with Medpor implant. The Correction of the eyelid coloboma was obtained by transposition and advancement of a superior palpebral flap. Results All operations were successful. In all of the patients improved facial contour and symmetry had been. No function disorder were found.Follow-up ranged from 3 months to 5 years. There have been no complications, such as infection and implant exclusion. Conclusion Orbitozygomatic reconstruction and musculocutaneous flap transposition from the upper eyelid offers a stable and predictable technique for improving ocular malformations. It is the most important treatment for Treacher Collins syndrome. Medpor appears no donor injury.