摘要
目的:验证前列安颗粒疗效为临床用药提供依据。方法:①对1·5%角叉菜胶致大鼠非细菌性前列腺炎的影响;②对二甲苯致小鼠耳肿胀的影响;③0·6%醋酸致小鼠腹腔毛细血管通透性的影响。结果:前列安颗粒可抑制角叉菜胶所致大鼠前列腺非细菌性炎症,增加前列腺组织内卵磷脂小体密度,并可明显抑制棉球肉芽肿形成;对二甲苯所致小鼠炎症均有明显抑制作用;可明显抑制0·6%醋酸所致小鼠腹腔毛细血管通透性的增加。结论:前列安颗粒具有明显抑制前列腺炎的作用。
Objective:to Verify the curative effect of Qianliean Granule and to provide the basis for clinical administration. Methods: 1. effect on nonbacterial prostatitis induced by 1.5% carrageenan; 2. effect on xylene-induced mouse ear swelling; 3. effect on mouse peritoneal capillary permeability induced by 0.6% acetic acid. Results: Qianliean Granule could inhibit nonbacterial prostatitis induced by carrageenan; increase lecithin density in prostate tissues; significantly inhibit Cotton granuloma formation; had inhibitive effect on xylene-induced inflammation; and significantly inhibit the increase of mouse peritoneal capillary permeability induced by 0.6% acetic acid. Conclusion: Qianliean Granules is able to inhibit prostatitis.
出处
《河北中医药学报》
2008年第1期3-6,共4页
Journal of Hebei Traditional Chinese Medicine and Pharmacology
基金
河北省科技厅资助项目:No04276416
关键词
前列安颗粒
慢性前列腺炎
药效学
Qianliean Granule
chronic prostatitis
Pharmacodynamics