摘要
目的:观察电针足三里穴对运动大鼠胃黏膜溃疡分数及外周血、延髓、胃窦组织中胃泌素(GAS)、内皮素(ET)含量的影响,以初步探讨电针对运动应激性溃疡的防治作用及其机制。方法:选用雄性SD大鼠24只,随机分成3组:对照组、运动应激组、电针组,采用放免法测定外周血、延髓、胃窦组织中胃泌素(GAS)、内皮素(ET)含量。结果:运动应激组溃疡分数极显著高于对照组(P<0.01),而电针组极显著低于运动组(P<0.01)。运动应激组大鼠外周血、延髓、胃窦组织中胃泌素(GAS)、内皮素(ET)含量明显高于对照组(P<0.01或P<0.05),电针组外周血、延髓、胃窦GAS、ET含量明显低于运动组(P<0.01,P<0.05),且与对照组比较含量无显著性差异。结论:电针足三里穴对运动应激性溃疡有防治作用,其机制可能与ET、GAS参与,减少胃酸分泌,增加胃黏膜血流量,致使大鼠溃疡分数降低,实现了调节胃功能的作用。
The purpose of this study is to investigate the effects of electro-acupuncture （EA） of ＂zu san li＂ on brain-gut peptide contents in medulla, blood and antrum of rats with exercise- induced stress. 24 male Sprague-Dawley rats were randomly divided into 3 groups., control group （CG）, exercise stress group （ESG） and electro-acupuncture （EA） group, the levels of GAS, ET in medulla, blood and antrum were measured by radioimmunoassay method. The result shows that in the exercise stress group （ESG）, the levels of GAS, ET in medulla, blood and antrum increased （P〈0.01 or P〈0.05）, UI increased （P〈0. 01） as compared with those of control group. In the electro-acupuncture （EA） group compared with exercise stress group, the levels of GAS, ET in medulla, blood and antrum decreased （P〈0.01 orp, 0.05）, UI decreased （P〉0.01）, In the EA group compared with control group the levels of GAS, ET had no significant changes. It concludes that EA has a marked protective action in exercise stress rats. This faction may be related to brain-gut peptide. EA at ＂zu san li＂ can evidently function in suppressing release of GAS, ET and suppressing gastric acid secretion and making GMBF increase, and decreasing UI as well as regulating gastrointestinal functions.
出处
《中国体育科技》
CSSCI
北大核心
2008年第2期133-135,143,共4页
China Sport Science and Technology
