BNP与ACC/AHA指南评估老年非心脏手术心血管事件比较分析

Analysis of Predictive Value of BNP and ACC/AHA Guideline for Cardiac Outcome after Senile Non-cardiac Surgery

目的:探讨B型利钠肽(BNP)评估老年非心脏手术心血管事件的价值。方法:比较分析BNP与ACC/AHA指南两种方法对101例老年非心脏手术中评估心血管事件的价值。结果:对于心脏事件的发生,BNP水平>100 pg/m l与ACC/AHA指南中高危级评估相比,它的敏感性高(100%比92.9%),特异性高(70.1%比47.1%),阳性预测价值大(35%比22%),阴性预测价值大(100%比97.6%),准确率高(74.3%比53.4%),而假阳性率低(29.9%比52.9%),假阴性率低(0%比7.1%)。结论:血浆BNP浓度>100 pg/m l较ACC/AHA指南中高危级评估对老年非心脏手术心血管事件有更好的评估价值。

Objective：To explore the predictive value of BNP and ACC/AHA guideline for cardiac outcome after senile non-cardiac surgery. Methods ：To analyze the predictive value of BNP and American College of Cardiology （ACC）/ American Heart Assocation（AHA） guideline for cardiac outcome after non-cardiac surgery in 101 old aged patients. Resuits ：Compared with the high and moderate risk evaluation by ACC/AHA guideline, the BNP concentration〉100 pg/ml had a greater sensitivity（100%vs 92.9%）, specificity（70.1% vs 47.1 %）, positive predictive value（35%vs 22%） negative predictive value （100% vs 97.6 %） and accuracy （74.3 %vs 53.4 %） for cardiac events, but a inferior false positive （29.9% vs 52. 9%）and false positive 0%vs 7. 1%）.Conclusion：A BNP concentration 〉100 pg/ml is better than the high and moderate risk evaluation by ACC/AHA guideline in predicting cardiac outcome after senile non cardiac surgery.