急性心肌梗死患者血清CTnI、D-D、CRP、UA、CK-MB联合检测的临床价值研究

Clinical evaluation for combined determination CtnI,D-D,CRP,UA and CK-MB in patients with acute myocardial infarction: a preliminary discussion

目的观察急性心肌梗死(AM I)患者发病初期肌钙蛋白I(CTnI)、D-二聚体(D-D)、C-反应蛋白(CRP)、尿酸(UA)、心肌型肌酸激酶(CK-MB)水平,探讨其临床意义。方法测定40例急性心肌梗死患者血清CTnI、D-D、CRP、UA、CK-MB的含量和活性,并与冠心病(CHD)组和正常对照组比较。结果AM I组的CTnI、D-D、CRP、UA、CK-MB检测阳性率明显高于冠心病组和健康对照组(P<0.01)。结论CTnI、D-D、CRP、UA、CK-MB各自的特点不同,联合检测在AM I诊断中具有重要的临床意义。

Objective： To evaluate the clinical significance of cardiac troponin I（ CTnI）, D-Dimer（ D-D）, C-reactive protein（ CRP）, UA, myocardial creatine kinase （CK - MB） level （CK-MB） in patients with acute myocardial infarction. Methods： The levels of CTnI, D-D, CRP, UA, CK-MB of 40 patients were determined at the early stage of acute myocardial infarction, compared with those in coronary heart disease （CHD）group and then control group. Results： The positive rates of CTnI, D-D, CRP, UA, CK-MB in AMI group were all higher than those in the other groups（P 〈0.01 ）. Conclusion： Combined determination of CTnI, D-D, CRP, UA and CK-MB is important for the diagnosis of AMI.