摘要
目的:为了寻找算盘子(Clochidion puberum)的活性成分,对其化学成分进行研究。方法:采用硅胶柱层析和葡聚糖凝胶柱层析分离纯化技术,通过理化性质和波谱特征分离并鉴定化合物。结果:从乙醇提取物的石油醚萃取部位分离得到了2个化合物:3β,19α,23α-三羟基-12-烯-28-齐墩果酸(Ⅰ),2β,3β,23α-三羟基-12-烯-28-齐墩果酸(Ⅱ)。结论:以上化合物是从该植物地上部分中分离得到三萜化合物。
Objective: To study the chemical constituents from G. puberum, aiming at searching for bioactive natural products. Methods: Column chromatography techniques were used for separation and purification of the compounds and extensive spectral analyses spectrum were employed for structural elucidation, Results: Two compounds were isolated from the aerial part of G. puberum and their structures were identified as: 3β,19α, 23α-trihydroxy-12-oleanen-28-oic acid ( Ⅰ ), 2β, 3β, 23α-trihydroxy-12-oleanen- 28-oic acid ( Ⅱ ), Conclusion: All compounds were isolated from the aerial part of this plant.
关键词
算盘子
化学成分
三萜
Glochidion puberum
chemical constituents
triterpenoids