男性肛周尖锐湿疣58例临床特征及治疗观察

Clinical Features and Their Treatment of Peri-anai Condyioma Acuminatum of 58 Male Patients

为了解男性肛周尖锐湿疣的临床特征及治疗效果，总结58例男性肛周尖锐湿疣临床特征及治疗效果。本组患者年龄3-74岁，主要见于20-50岁（共47例，占81.03％）。肛门直肠疾病如肛门瘙痒、肛门湿疹、肛裂及痔疮等均可出现局部皮肤黏膜的破坏，而为人乳头瘤病毒感染创造条件。其中经典型尖锐湿疣54例（93.10％），扁平型尖锐湿疣4例（6.90％），合并直肠尖锐湿疣42例（72.41％）。直肠尖锐湿疣选冷冻治疗，肛周尖锐湿疣应用100万U a2 b-干扰素瘤体根部局部封闭，隔日1次共10次，转移因子100万U肌肉注射，隔日1次共6次。局部电凝、激光或冷冻法去除瘤体，除5例3个月后复发外，其余一次治愈。

In order to understand the clinical features and curative effects of male peri-anal condyloma acuminatum,author summurized the data of 58 male patients with the disease. Results showed that this disease maily distrubuted at the male patients from 20 to 50 yr. （47/58,81.03%）. In ano-rectal diseases such as anal prurities, anal eczema, anal fissure and hemorrhoids there all were local skin, mucous membrane lesion, thus inducing infection of papillomavirus. Among the 58 cases, classic condyloma acuminatum was in 54 cases（93.10%） ,flat condyloma in 4 cases（6.90%）;complicated with rectal condyloma acuminatum in 42 cases（72.40%）. For rectal condyloma acuminatum cryotherapy was adopted,for peri-anal condyloma acumi- natum local blocking therapy with 1 million U of α-2b interferon at the tumor-body root site,1 time/2days, totally 10 times ; 1 million U of γ-interferon was injected intramuscularly, 1 time/2days, totally 6 times ; local electri coagulation,laser or cryotherapy were used to remove tumor-body. Except for 5 cases being recurrence later 3 monthes after above treatment,rest cases were all cured primarily.