毛金竹叶提取物抗衰老作用的实验研究

Experimental studies on anti-aging effect of the leaf-extract of Ph. nigra var. henonis

用昆明种小鼠作为试验对象，研究了毛金竹叶提取物（LE）抗衰老的生物学效应。结果表明：高剂量组的LE能显著增强小鼠对非特异性刺激的抵抗能力（常压耐缺氧试验，p＜0．01）和抗疲劳能力（游泳试验，P＜0．01）；对正常小鼠的学习能力有一定的促进作用（电迷路法，p＜（0．05）；对老年小鼠体内的超氧化物歧化酶（SOD）和谷胱苷肽过氧化物酶（GSH－Px）活性有显著的诱导作用；并且明显抑制了老年小鼠血浆过氧化脂质（LPO）的生成、降低了肝脏脂褐素（LF）的含量等。研究结果提示LE具有一定的抗衰老作用，竹叶可以作为一种抗衰老功能因子的新资源加以研究和开发。

This paper investigated the anti-aging effect of the leaf-extract (LE) of Ph. nigra var. henonis on experimental mice. The results showed that LE could enhance the capacity of anti-fatigue and resistance to nonspecific irritation of mice,and improve their studyingability obviously. LE also could induce the activity of SOD and GSH-Px,inhibit the post-oxidation of lipid and scavenge post-oxidated products of aged mice,etc.,Bamboo leaves can befurther studied and developed as a kind of new resources of anti-aging functional factors.